5UKR

Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab in complex with a gp120 core

Summary for 5UKR

• Entry DOI: 10.2210/pdb5ukr/pdb
• Related: 5UKN 5UKO 5UKP 5UKQ
• Descriptor: DH522.2 Fab fragment heavy chain, DH522.2 Fab fragment light chain, Chimeric B.YU2 gp120 core derived from HIV-1 Env, ... (5 entities in total)
• Functional Keywords: hiv gp120 immune system, immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 3
• Total formula weight: 83451.28

Authors

Nicely, N.I. (deposition date: 2017-01-23, release date: 2017-12-06, Last modification date: 2023-10-04)

• Primary citation: Williams, W.B.,Zhang, J.,Jiang, C.,Nicely, N.I.,Fera, D.,Luo, K.,Moody, M.A.,Liao, H.X.,Alam, S.M.,Kepler, T.B.,Ramesh, A.,Wiehe, K.,Holland, J.A.,Bradley, T.,Vandergrift, N.,Saunders, K.O.,Parks, R.,Foulger, A.,Xia, S.M.,Bonsignori, M.,Montefiori, D.C.,Louder, M.,Eaton, A.,Santra, S.,Scearce, R.,Sutherland, L.,Newman, A.,Bouton-Verville, H.,Bowman, C.,Bomze, H.,Gao, F.,Marshall, D.J.,Whitesides, J.F.,Nie, X.,Kelsoe, G.,Reed, S.G.,Fox, C.B.,Clary, K.,Koutsoukos, M.,Franco, D.,Mascola, J.R.,Harrison, S.C.,Haynes, B.F.,Verkoczy, L.; Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.; Nat Commun, 8:1732-1732, 2017; PubMed: 29170366; DOI: 10.1038/s41467-017-01336-3

Experimental method

X-RAY DIFFRACTION (2.712 Å)