5UG6
Perforin C2 Domain - T431D
Summary for 5UG6
Entry DOI | 10.2210/pdb5ug6/pdb |
Related | 5UG7 |
Descriptor | Perforin-1, IODIDE ION (3 entities in total) |
Functional Keywords | c2, perforin, calcium, proteostasis, apoptosis |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 16615.98 |
Authors | Law, R.H.P.,Conroy, P.J.,Voskoboinik, I.,Whisstock, J.C. (deposition date: 2017-01-07, release date: 2018-02-07, Last modification date: 2023-10-04) |
Primary citation | Brennan, A.J.,Law, R.H.P.,Conroy, P.J.,Noori, T.,Lukoyanova, N.,Saibil, H.,Yagita, H.,Ciccone, A.,Verschoor, S.,Whisstock, J.C.,Trapani, J.A.,Voskoboinik, I. Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25:1517-1529, 2018 Cited by PubMed: 29416110DOI: 10.1038/s41418-018-0057-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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