5UFZ

HIV-1 Protease complexed with Inhibitor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2S)-1-(1-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}cyclopropyl)-1-hydroxy-3-phenylpropan-2-yl]carbamate

5UFZ の概要

• エントリーDOI: 10.2210/pdb5ufz/pdb
• 分子名称: Protease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2S)-1-(1-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}cyclopropyl)-1-hydroxy-3-phenylpropan-2-yl]carbamate (3 entities in total)
• 機能のキーワード: hiv-1 protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22237.32

構造登録者

Zachary, N.E.R. (登録日: 2017-01-06, 公開日: 2018-01-10, 最終更新日: 2024-03-06)

• 主引用文献: Mitchell, M.L.,Xu, L.,Zachary, N.E.R.,Desai, M.C.; Synthesis of Novel HIV-1 Protease Inhibitors via Diasteroselective Henry Reaction with Nitrocyclopropane; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (1.649 Å)