5UFM

Crystal structure of Burkholderia thailandensis 1,6-didemethyltoxoflavin-N1-methyltransferase with bound 1,6-didemethyltoxoflavin and S-adenosylhomocysteine

5UFM の概要

• エントリーDOI: 10.2210/pdb5ufm/pdb
• 関連するPDBエントリー: 5UFN
• 分子名称: Methyltransferase domain protein, S-ADENOSYL-L-HOMOCYSTEINE, pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione, ... (6 entities in total)
• 機能のキーワード: transferase, n-methyltransferase, s-adenosylmethionine-dependent
• 由来する生物種: Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55313.24

構造登録者

Fenwick, M.K.,Ealick, S.E.,Almabruk, K.H.,Begley, T.P.,Philmus, B. (登録日: 2017-01-05, 公開日: 2017-12-13, 最終更新日: 2024-03-06)

• 主引用文献: Fenwick, M.K.,Almabruk, K.H.,Ealick, S.E.,Begley, T.P.,Philmus, B.; Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.; Biochemistry, 56:3934-3944, 2017; PubMed: 28665591; DOI: 10.1021/acs.biochem.7b00476

実験手法

X-RAY DIFFRACTION (1.77 Å)