5UEN
Crystal structure of the human adenosine A1 receptor A1AR-bRIL in complex with the covalent antagonist DU172 at 3.2A resolution
Summary for 5UEN
Entry DOI | 10.2210/pdb5uen/pdb |
Descriptor | Adenosine receptor A1,Soluble cytochrome b562,Adenosine receptor A1, 4-{[3-(8-cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-3H-purin-3-yl)propyl]carbamoyl}benzene-1-sulfonyl fluoride, OLEIC ACID (3 entities in total) |
Functional Keywords | gpcr, transmembrane, receptor, adenosine, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 96136.47 |
Authors | Glukhova, A.,Thal, D.M.,Nguyen, A.T.,Vecchio, E.A.,Jorg, M.,Scammells, P.J.,May, L.T.,Sexton, P.M.,Christopoulos, A. (deposition date: 2017-01-03, release date: 2017-03-01, Last modification date: 2023-10-04) |
Primary citation | Glukhova, A.,Thal, D.M.,Nguyen, A.T.,Vecchio, E.A.,Jorg, M.,Scammells, P.J.,May, L.T.,Sexton, P.M.,Christopoulos, A. Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity. Cell, 168:867-877.e13, 2017 Cited by PubMed: 28235198DOI: 10.1016/j.cell.2017.01.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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