5UDY
Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7)
Summary for 5UDY
| Entry DOI | 10.2210/pdb5udy/pdb |
| Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
| Functional Keywords | sphingomyelinase, sphingomyelin, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 53346.49 |
| Authors | Gorelik, A.,Liu, F.,Illes, K.,Nagar, B. (deposition date: 2016-12-28, release date: 2017-03-22, Last modification date: 2020-07-29) |
| Primary citation | Gorelik, A.,Liu, F.,Illes, K.,Nagar, B. Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. J. Biol. Chem., 292:7087-7094, 2017 Cited by PubMed: 28292932DOI: 10.1074/jbc.M116.769273 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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