5UBM

Crystal structure of human C1s in complex with inhibitor gigastasin

5UBM の概要

• エントリーDOI: 10.2210/pdb5ubm/pdb
• 分子名称: Complement C1s subcomponent, Gigastasin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: complement system c1s protease inhibitor complex, immune system-inhibitor complex, immune system/inhibitor
• 由来する生物種: Haementeria ghilianii; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 61253.12

構造登録者

Pang, S.S.,Whisstock, J.C. (登録日: 2016-12-20, 公開日: 2017-11-08, 最終更新日: 2023-11-15)

• 主引用文献: Pang, S.S.,Wijeyewickrema, L.C.,Hor, L.,Tan, S.,Lameignere, E.,Conway, E.M.,Blom, A.M.,Mohlin, F.C.,Liu, X.,Payne, R.J.,Whisstock, J.C.,Pike, R.N.; The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.; J. Immunol., 199:3883-3891, 2017; PubMed: 29061764; DOI: 10.4049/jimmunol.1700158

実験手法

X-RAY DIFFRACTION (2.5 Å)