5U9J

Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with geranyl geranyl pyrophoshate

Summary for 5U9J

• Entry DOI: 10.2210/pdb5u9j/pdb
• Related: 5U9A 5U9I 5U9K
• Descriptor: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), GERAN-8-YL GERAN, ISOPROPYL ALCOHOL, ... (5 entities in total)
• Functional Keywords: aipl1, fkbp, chaperone, pde6, photoreceptor, lca, isoprenyl, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 39286.27

Authors

Yadav, R.P.,Gakhar, L.,Liping, Y.,Artemyev, N.O. (deposition date: 2016-12-16, release date: 2017-07-26, Last modification date: 2023-10-04)

• Primary citation: Yadav, R.P.,Gakhar, L.,Yu, L.,Artemyev, N.O.; Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.; Proc. Natl. Acad. Sci. U.S.A., 114:E6536-E6545, 2017; PubMed: 28739921; DOI: 10.1073/pnas.1704782114

Experimental method

X-RAY DIFFRACTION (2.1 Å)