5U98
The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01
Summary for 5U98
Entry DOI | 10.2210/pdb5u98/pdb |
Descriptor | HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, VAL-THR-THR-ASP-ILE-GLN-VAL-LYS-VAL, ... (5 entities in total) |
Functional Keywords | mhc, antigen presenting cell, t-cell receptor, human leukocyte antigen, drug hypersensitivity, abacavir hypersensitivity, repertoire-altering small molecule, immune response, immunoglobulin-like beta-sandwich, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 89810.05 |
Authors | Ostrov, D.A.,Bracey, A.W.,Pompeu, Y.A.,Jakoncic, J.,Buus, S.,Buus, A.S.,Schutte, R.J. (deposition date: 2016-12-15, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Yerly, D.,Pompeu, Y.A.,Schutte, R.J.,Eriksson, K.K.,Strhyn, A.,Bracey, A.W.,Buus, S.,Ostrov, D.A. Structural Elements Recognized by Abacavir-Induced T Cells. Int J Mol Sci, 18:-, 2017 Cited by PubMed: 28686208DOI: 10.3390/ijms18071464 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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