5U26

Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p218 Inhibitor

5U26 の概要

• エントリーDOI: 10.2210/pdb5u26/pdb
• 分子名称: Dihydrofolate reductase, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: dhfr, folate, structural genomics, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21190.37

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2016-11-29, 公開日: 2016-12-21, 最終更新日: 2023-10-04)

• 主引用文献: Mayclin, S.J.,Fairman, J.W.,Lorimer, D.D.,Edwards, T.E.; Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p218 Inhibitor; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (1.85 Å)