5TZV

Binary complex crystal structure of DNA Polymerase Beta with G:T mismatch at the primer terminus

Replaces:  5J0V

Summary for 5TZV

• Entry DOI: 10.2210/pdb5tzv/pdb
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase, fidelity, mismatch extension, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 47798.84

Authors

Wilson, S.H.,Batra, V.K. (deposition date: 2016-11-22, release date: 2016-12-07, Last modification date: 2023-10-04)

• Primary citation: Batra, V.K.,Beard, W.A.,Pedersen, L.C.,Wilson, S.H.; Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.; Structure, 24:1863-1875, 2016; PubMed: 27642161; DOI: 10.1016/j.str.2016.08.006

Experimental method

X-RAY DIFFRACTION (2 Å)