5TZO
Computationally Designed Fentanyl Binder - Fen49*-Complex
Summary for 5TZO
Entry DOI | 10.2210/pdb5tzo/pdb |
Related | 5TVV 5TVY |
Descriptor | Endo-1,4-beta-xylanase A, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | computational design, fentanyl, hydrolase |
Biological source | Bacillus subtilis (strain 168) |
Total number of polymer chains | 3 |
Total formula weight | 63542.22 |
Authors | Bick, M.J.,Greisen, P.J.,Morey, K.J.,Antunes, M.S.,La, D.,Sankaran, B.,Reymond, L.,Johnsson, K.,Medford, J.I.,Baker, D. (deposition date: 2016-11-22, release date: 2017-10-04, Last modification date: 2024-03-06) |
Primary citation | Bick, M.J.,Greisen, P.J.,Morey, K.J.,Antunes, M.S.,La, D.,Sankaran, B.,Reymond, L.,Johnsson, K.,Medford, J.I.,Baker, D. Computational design of environmental sensors for the potent opioid fentanyl. Elife, 6:-, 2017 Cited by PubMed: 28925919DOI: 10.7554/eLife.28909 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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