5TZ6
Crystal Structure of CurJ Dehydratase H978F Inactive Mutant In Complex with Compound 21
Summary for 5TZ6
Entry DOI | 10.2210/pdb5tz6/pdb |
Related | 5TZ5 5TZ7 |
Descriptor | CurJ, (2E,5R)-5-hydroxy-2-methylhept-2-enoic acid (3 entities in total) |
Functional Keywords | dehydratase, curacin, polyketide synthase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Moorea producens 3L |
Total number of polymer chains | 2 |
Total formula weight | 69326.17 |
Authors | Dodge, G.J.,Smith, J.L. (deposition date: 2016-11-21, release date: 2017-01-11, Last modification date: 2023-10-04) |
Primary citation | Fiers, W.D.,Dodge, G.J.,Sherman, D.H.,Smith, J.L.,Aldrich, C.C. Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis. J. Am. Chem. Soc., 138:16024-16036, 2016 Cited by PubMed: 27960309DOI: 10.1021/jacs.6b09748 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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