5TYT
Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
Summary for 5TYT
Entry DOI | 10.2210/pdb5tyt/pdb |
Descriptor | Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera (2 entities in total) |
Functional Keywords | pdz-rhogef, cxcr2, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P25025 |
Total number of polymer chains | 4 |
Total formula weight | 37423.72 |
Authors | Spellmon, N.,Holcomb, J.,Niu, A.,Choudhary, V.,Sun, X.,Brunzelle, J.,Li, C.,Yang, Z. (deposition date: 2016-11-21, release date: 2017-02-22, Last modification date: 2023-10-04) |
Primary citation | Spellmon, N.,Holcomb, J.,Niu, A.,Choudhary, V.,Sun, X.,Zhang, Y.,Wan, J.,Doughan, M.,Hayden, S.,Hachem, F.,Brunzelle, J.,Li, C.,Yang, Z. Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. Biochem. Biophys. Res. Commun., 485:529-534, 2017 Cited by PubMed: 28179147DOI: 10.1016/j.bbrc.2017.02.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.398 Å) |
Structure validation
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