5TVB

Structure of the TPR oligomerization domain

Summary for 5TVB

• Entry DOI: 10.2210/pdb5tvb/pdb
• Descriptor: Nucleoprotein TPR (2 entities in total)
• Functional Keywords: receptor tyrosine kinase, oncogenic fusion kinases, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P12270
• Total number of polymer chains: 2
• Total formula weight: 33813.29

Authors

Pal, K.,Xu, Q.,Zhou, X.E.,Melcher, K.,Xu, H.E. (deposition date: 2016-11-08, release date: 2017-09-20, Last modification date: 2017-11-01)

• Primary citation: Pal, K.,Bandyopadhyay, A.,Zhou, X.E.,Xu, Q.,Marciano, D.P.,Brunzelle, J.S.,Yerrum, S.,Griffin, P.R.,Vande Woude, G.,Melcher, K.,Xu, H.E.; Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.; Structure, 25:867-877.e3, 2017; PubMed: 28528776; DOI: 10.1016/j.str.2017.04.015

Experimental method

X-RAY DIFFRACTION (2.75 Å)