5TPW

Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A

Summary for 5TPW

Entry DOI	10.2210/pdb5tpw/pdb
Related	5TPZ 5TQ0 5TQ2
Descriptor	NMDA glutamate receptor subunit, Glutamate receptor ionotropic, NMDA 2A, FAB, HEAVY CHAIN, ... (9 entities in total)
Functional Keywords	ion channel, nmda receptor, allosteric modulation, zinc inhibition, transport protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	4
Total formula weight	132949.11
Authors	Romero-Hernandez, A.,Simorowski, N.,Karakas, E.,Furukawa, H. (deposition date: 2016-10-21, release date: 2016-12-14, Last modification date: 2023-10-04)
Primary citation	Romero-Hernandez, A.,Simorowski, N.,Karakas, E.,Furukawa, H. Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Neuron, 92:1324-1336, 2016 Cited by PubMed: 27916457 DOI: 10.1016/j.neuron.2016.11.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.909 Å)

Structure validation