5TOJ
Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4
Summary for 5TOJ
Entry DOI | 10.2210/pdb5toj/pdb |
Related | 5TOK |
Descriptor | Fusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-4, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | fusion, nanobody, immunoglobulin fold, complex, viral protein-immune system complex, viral protein/immune system |
Biological source | Human respiratory syncytial virus More |
Total number of polymer chains | 6 |
Total formula weight | 227109.53 |
Authors | Gilman, M.S.A.,Kabeche, S.C.,McLellan, J.S. (deposition date: 2016-10-17, release date: 2017-02-22, Last modification date: 2023-10-04) |
Primary citation | Rossey, I.,Gilman, M.S.,Kabeche, S.C.,Sedeyn, K.,Wrapp, D.,Kanekiyo, M.,Chen, M.,Mas, V.,Spitaels, J.,Melero, J.A.,Graham, B.S.,Schepens, B.,McLellan, J.S.,Saelens, X. Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8:14158-14158, 2017 Cited by PubMed: 28194013DOI: 10.1038/ncomms14158 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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