5TMP
COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR AZTP5A
Summary for 5TMP
Entry DOI | 10.2210/pdb5tmp/pdb |
Descriptor | PROTEIN (THYMIDYLATE KINASE), P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE (3 entities in total) |
Functional Keywords | atp:dtmp phosphotransferase, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 24739.49 |
Authors | Lavie, A.,Ostermann, N.,Schlichting, I. (deposition date: 1998-09-01, release date: 1998-11-25, Last modification date: 2023-12-27) |
Primary citation | Lavie, A.,Ostermann, N.,Brundiers, R.,Goody, R.S.,Reinstein, J.,Konrad, M.,Schlichting, I. Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proc.Natl.Acad.Sci.USA, 95:14045-14050, 1998 Cited by PubMed: 9826650DOI: 10.1073/pnas.95.24.14045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
Download full validation report