5TJZ

Structure of 4-Hydroxytetrahydrodipicolinate Reductase from Mycobacterium tuberculosis with NADPH and 2,6 Pyridine Dicarboxylic Acid

5TJZ の概要

• エントリーDOI: 10.2210/pdb5tjz/pdb
• 関連するPDBエントリー: 5TJY
• 分子名称: 4-hydroxy-tetrahydrodipicolinate reductase, PYRIDINE-2,6-DICARBOXYLIC ACID, BENZOIC ACID, ... (10 entities in total)
• 機能のキーワード: oxidoreductase, lysine biosynthesis
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
• 細胞内の位置: Cytoplasm : A5U6C6
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27679.20

構造登録者

Mank, N.J.,Arnette, A.K.,Klapper, V.,Chruszcz, M. (登録日: 2016-10-05, 公開日: 2018-01-10, 最終更新日: 2023-10-04)

• 主引用文献: Pote, S.,Kachhap, S.,Mank, N.J.,Daneshian, L.,Klapper, V.,Pye, S.,Arnette, A.K.,Shimizu, L.S.,Borowski, T.,Chruszcz, M.; Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus.; Biochim Biophys Acta Gen Subj, 1865:129750-129750, 2021; PubMed: 32980502; DOI: 10.1016/j.bbagen.2020.129750

実験手法

X-RAY DIFFRACTION (1.5 Å)