5TJA

I-II linker of TRPML1 channel at pH 6

Summary for 5TJA

Entry DOI	10.2210/pdb5tja/pdb
Related	5TJB 5TJC
Descriptor	Mucolipin-1 (2 entities in total)
Functional Keywords	endolysosomal lumen, tetramer, calcium and ph regulation, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	25195.06
Authors	Li, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J. (deposition date: 2016-10-04, release date: 2017-01-25, Last modification date: 2019-12-18)
Primary citation	Li, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J. Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24:205-213, 2017 Cited by PubMed: 28112729 DOI: 10.1038/nsmb.3362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation