5TIF

x-ray structure of acyl-CoA thioesterase I, TesA, triple mutant M141L/Y145K/L146K in complex with octanoic acid

5TIF の概要

• エントリーDOI: 10.2210/pdb5tif/pdb
• 関連するPDBエントリー: 5TIC 5tid 5tie
• 分子名称: Acyl-CoA thioesterase I, OCTANOIC ACID (CAPRYLIC ACID), DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• 機能のキーワード: thioesterase, tesa, fatty acid, octanoic acid, hydrolase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20935.86

構造登録者

Thoden, J.B.,Holden, H.M.,Grisewood, M.J.,Hernandez Lozada, N.J.,Gifford, N.P.,Mendez-Perez, D.,Schoenberger, H.A.,Allan, M.F.,Pfleger, B.F.,Marines, C.D. (登録日: 2016-10-02, 公開日: 2017-04-26, 最終更新日: 2023-10-04)

• 主引用文献: Grisewood, M.J.,Hernandez Lozada, N.J.,Thoden, J.B.,Gifford, N.P.,Mendez-Perez, D.,Schoenberger, H.A.,Allan, M.F.,Floy, M.E.,Lai, R.Y.,Holden, H.M.,Pfleger, B.F.,Maranas, C.D.; Computational Redesign of Acyl-ACP Thioesterase with Improved Selectivity toward Medium-Chain-Length Fatty Acids.; ACS Catal, 7:3837-3849, 2017; PubMed: 29375928; DOI: 10.1021/acscatal.7b00408

実験手法

X-RAY DIFFRACTION (0.97 Å)