5TI9
Crystal structure of human TDO in complex with Trp and dioxygen, Northeast Structural Genomics Consortium Target HR6161
Summary for 5TI9
Entry DOI | 10.2210/pdb5ti9/pdb |
Related | 5TIA |
Descriptor | Tryptophan 2,3-dioxygenase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total) |
Functional Keywords | human tryptophan 2, 3-dioxygenase in complex with trp and o2, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 185147.83 |
Authors | Forouhar, F.,Lewis-Ballester, A.,Lew, S.,Karkashon, S.,Seetharaman, J.,Yeh, S.R.,Tong, L. (deposition date: 2016-10-01, release date: 2016-10-26, Last modification date: 2023-11-15) |
Primary citation | Lewis-Ballester, A.,Forouhar, F.,Kim, S.M.,Lew, S.,Wang, Y.,Karkashon, S.,Seetharaman, J.,Batabyal, D.,Chiang, B.Y.,Hussain, M.,Correia, M.A.,Yeh, S.R.,Tong, L. Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase. Sci Rep, 6:35169-35169, 2016 Cited by PubMed: 27762317DOI: 10.1038/srep35169 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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