5THU
Crystal Structure of G304A HDAC8 in complex with M344
Summary for 5THU
Entry DOI | 10.2210/pdb5thu/pdb |
Related | 5THS 5THT 5THV |
Descriptor | Histone deacetylase 8, ZINC ION, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | zinc histone deacetylase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 87583.19 |
Authors | Porter, N.J.,Christianson, D.W. (deposition date: 2016-09-30, release date: 2016-12-21, Last modification date: 2023-10-04) |
Primary citation | Porter, N.J.,Christianson, N.H.,Decroos, C.,Christianson, D.W. Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. Biochemistry, 55:6718-6729, 2016 Cited by PubMed: 27933794DOI: 10.1021/acs.biochem.6b01014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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