5TGD

Crystal structure of FolM Alternative dihydrofolate reductase 1 from Brucella suis in complex with NADP

Summary for 5TGD

Entry DOI	10.2210/pdb5tgd/pdb
Descriptor	FolM Alternative dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	ssgcid, oxidoreductase, short chain dehydrogenase/reductase family, dihydrofolate reductase, nadp, brucella suis, structural genomics, seattle structural genomics center for infectious disease
Biological source	Brucella suis 92/29
Total number of polymer chains	4
Total formula weight	122089.14
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2016-09-27, release date: 2016-10-12, Last modification date: 2023-10-04)
Primary citation	Porter, I.,Neal, T.,Walker, Z.,Hayes, D.,Fowler, K.,Billups, N.,Rhoades, A.,Smith, C.,Smith, K.,Staker, B.L.,Dranow, D.M.,Mayclin, S.J.,Subramanian, S.,Edwards, T.E.,Myler, P.J.,Asojo, O.A. Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis. Acta Crystallogr.,Sect.F, 78:31-38, 2022 Cited by PubMed: 34981773 DOI: 10.1107/S2053230X21013078 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation