5TFS

Structure of chimeric 02-K Fab, a VRC01-like germline antibody

Summary for 5TFS

• Entry DOI: 10.2210/pdb5tfs/pdb
• Related: 5TF1 5TGB
• Descriptor: 02-K Fab Heavy chain, 02-K Fab Light chain, SULFATE ION, ... (4 entities in total)
• Functional Keywords: fab, hiv-1, vrc01, cdrh3, cd4-bs, vh1-2, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 46846.11

Authors

Pancera, M. (deposition date: 2016-09-26, release date: 2016-11-09, Last modification date: 2019-12-11)

• Primary citation: Yacoob, C.,Pancera, M.,Vigdorovich, V.,Oliver, B.G.,Glenn, J.A.,Feng, J.,Sather, D.N.,McGuire, A.T.,Stamatatos, L.; Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.; Cell Rep, 17:1560-1570, 2016; PubMed: 27806295; DOI: 10.1016/j.celrep.2016.10.017

Experimental method

X-RAY DIFFRACTION (2.319 Å)