5TE0
Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with BIBF 1120
Summary for 5TE0
Entry DOI | 10.2210/pdb5te0/pdb |
Descriptor | AP2-associated protein kinase 1, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 40465.33 |
Authors | Counago, R.M.,Elkins, J.M.,Bountra, C.,Arruda, P.,Edwards, A.M.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2016-09-20, release date: 2016-11-02, Last modification date: 2023-10-04) |
Primary citation | Counago, R.M.,Elkins, J.M.,Arrowsmith, C.H.,Bountra, C.,Arruda, P.,Edwards, A.M.,Gileadi, O. Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with BIBF 1120 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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