5TE0

Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with BIBF 1120

5TE0 の概要

• エントリーDOI: 10.2210/pdb5te0/pdb
• 分子名称: AP2-associated protein kinase 1, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• 機能のキーワード: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40465.33

構造登録者

Counago, R.M.,Elkins, J.M.,Bountra, C.,Arruda, P.,Edwards, A.M.,Gileadi, O.,Structural Genomics Consortium (SGC) (登録日: 2016-09-20, 公開日: 2016-11-02, 最終更新日: 2023-10-04)

• 主引用文献: Counago, R.M.,Elkins, J.M.,Arrowsmith, C.H.,Bountra, C.,Arruda, P.,Edwards, A.M.,Gileadi, O.; Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with BIBF 1120; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)