5TCZ
NMR solution structure of engineered Protoxin-II analog
Summary for 5TCZ
Entry DOI | 10.2210/pdb5tcz/pdb |
NMR Information | BMRB: 30181 |
Descriptor | Beta/omega-theraphotoxin-Tp2a (1 entity in total) |
Functional Keywords | venom peptide analog, inhibitor, cystine knot, toxin |
Biological source | Thrixopelma pruriens (Peruvian green velvet tarantula) |
Total number of polymer chains | 1 |
Total formula weight | 3862.72 |
Authors | |
Primary citation | Flinspach, M.,Xu, Q.,Piekarz, A.D.,Fellows, R.,Hagan, R.,Gibbs, A.,Liu, Y.,Neff, R.A.,Freedman, J.,Eckert, W.A.,Zhou, M.,Bonesteel, R.,Pennington, M.W.,Eddinger, K.A.,Yaksh, T.L.,Hunter, M.,Swanson, R.V.,Wickenden, A.D. Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor. Sci Rep, 7:39662-39662, 2017 Cited by PubMed: 28045073DOI: 10.1038/srep39662 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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