5TCD
Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine
Summary for 5TCD
Entry DOI | 10.2210/pdb5tcd/pdb |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | sphingomyelinase, sphingomyelin, phosphocholine, glycosylphosphatidylinositol, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 55640.03 |
Authors | Gorelik, A.,Liu, F.,Illes, K.,Nagar, B. (deposition date: 2016-09-14, release date: 2017-03-22, Last modification date: 2020-07-29) |
Primary citation | Gorelik, A.,Liu, F.,Illes, K.,Nagar, B. Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. J. Biol. Chem., 292:7087-7094, 2017 Cited by PubMed: 28292932DOI: 10.1074/jbc.M116.769273 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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