5TCD

Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine

5TCD の概要

• エントリーDOI: 10.2210/pdb5tcd/pdb
• 分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: sphingomyelinase, sphingomyelin, phosphocholine, glycosylphosphatidylinositol, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55640.03

構造登録者

Gorelik, A.,Liu, F.,Illes, K.,Nagar, B. (登録日: 2016-09-14, 公開日: 2017-03-22, 最終更新日: 2020-07-29)

• 主引用文献: Gorelik, A.,Liu, F.,Illes, K.,Nagar, B.; Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.; J. Biol. Chem., 292:7087-7094, 2017; PubMed: 28292932; DOI: 10.1074/jbc.M116.769273

実験手法

X-RAY DIFFRACTION (2.4 Å)