5TC8
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with methylthio-DADMe-Immucillin-A
Summary for 5TC8
Entry DOI | 10.2210/pdb5tc8/pdb |
Related | 1K27 3OZC 3OZD 3OZE 5TC5 5TC6 5TC7 |
Descriptor | S-methyl-5'-thioadenosine phosphorylase, (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, PHOSPHATE ION, ... (8 entities in total) |
Functional Keywords | phosphorylase, inhibitor, complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34218.20 |
Authors | Cameron, S.A.,Firestone, R.S.,Schramm, V.L.,Almo, S.C. (deposition date: 2016-09-14, release date: 2017-10-11, Last modification date: 2023-10-04) |
Primary citation | Firestone, R.S.,Cameron, S.A.,Karp, J.M.,Arcus, V.L.,Schramm, V.L. TBA To be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report