5TC8

Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with methylthio-DADMe-Immucillin-A

Summary for 5TC8

• Entry DOI: 10.2210/pdb5tc8/pdb
• Related: 1K27 3OZC 3OZD 3OZE 5TC5 5TC6 5TC7
• Descriptor: S-methyl-5'-thioadenosine phosphorylase, (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, PHOSPHATE ION, ... (8 entities in total)
• Functional Keywords: phosphorylase, inhibitor, complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34218.20

Authors

Cameron, S.A.,Firestone, R.S.,Schramm, V.L.,Almo, S.C. (deposition date: 2016-09-14, release date: 2017-10-11, Last modification date: 2023-10-04)

• Primary citation: Firestone, R.S.,Cameron, S.A.,Karp, J.M.,Arcus, V.L.,Schramm, V.L.; TBA; To be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)