5TBT

Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with Cytidine

Summary for 5TBT

Entry DOI	10.2210/pdb5tbt/pdb
Related	5CXQ 5CXS 5KO5 5KO6 5TBS 5TBU 5TBV
Descriptor	Purine nucleoside phosphorylase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, SULFATE ION, ... (4 entities in total)
Functional Keywords	transferase
Biological source	Schistosoma mansoni (Blood fluke)
Total number of polymer chains	1
Total formula weight	31698.63
Authors	Faheem, M.,Torini, J.R.,Romanello, L.,Brandao-Neto, J.,Pereira, H.M. (deposition date: 2016-09-13, release date: 2017-10-11, Last modification date: 2023-10-04)
Primary citation	Torini, J.R.,Romanello, L.,Batista, F.A.H.,Serrao, V.H.B.,Faheem, M.,Zeraik, A.E.,Bird, L.,Nettleship, J.,Reddivari, Y.,Owens, R.,DeMarco, R.,Borges, J.C.,Brandao-Neto, J.,Pereira, H.D. The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13:e0203532-e0203532, 2018 Cited by PubMed: 30192840 DOI: 10.1371/journal.pone.0203532 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.101 Å)

Structure validation