5TBC

PRECATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE BETA WITH GAPPED DNA SUBSTRATE, INCORPORATED (-)3TC-MP AND AN ANOTHER INCOMING (-)3TC-TP NUCLEOTIDE.

Summary for 5TBC

• Entry DOI: 10.2210/pdb5tbc/pdb
• Related: 5TB8 5TB9 5TBA 5TBB
• Descriptor: DNA polymerase beta, 5-MER PHOSPHORYLATED DOWNSTREAM PRIMER, 10- MER PRIMER, ... (9 entities in total)
• Functional Keywords: x-family, pol beta, dna polymerase beta, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 49676.81

Authors

Vyas, R.,Suo, Z. (deposition date: 2016-09-11, release date: 2017-01-11, Last modification date: 2023-10-25)

• Primary citation: Reed, A.J.,Vyas, R.,Raper, A.T.,Suo, Z.; Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase.; J. Am. Chem. Soc., 139:465-471, 2017; PubMed: 27959534; DOI: 10.1021/jacs.6b11258

Experimental method

X-RAY DIFFRACTION (1.85 Å)