5T7Q
TIRAP phosphoinositide-binding motif
Summary for 5T7Q
| Entry DOI | 10.2210/pdb5t7q/pdb |
| NMR Information | BMRB: 30170 |
| Descriptor | Toll/interleukin-1 receptor domain-containing adapter protein (1 entity in total) |
| Functional Keywords | tirap, phosphoinositide, phosphorylation, phosphoinositide-binding motif; structure, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 2550.20 |
| Authors | Capelluto, D.G.S.,Ellena, J.F.,Armstrong, G.,Zhao, X.,Xiao, S. (deposition date: 2016-09-05, release date: 2017-03-08, Last modification date: 2023-06-14) |
| Primary citation | Zhao, X.,Xiong, W.,Xiao, S.,Tang, T.X.,Ellena, J.F.,Armstrong, G.S.,Finkielstein, C.V.,Capelluto, D.G. Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif. Sci Rep, 7:43043-43043, 2017 Cited by PubMed: 28225045DOI: 10.1038/srep43043 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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