5T4X
CRYSTAL STRUCTURE OF PDE6D IN APO-STATE
5T4X の概要
エントリーDOI | 10.2210/pdb5t4x/pdb |
分子名称 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (2 entities in total) |
機能のキーワード | immunoglobulin-like beta sandwitch, pde6 delta, farnesyl, lipid binding protein, prenyl binding protein, geranylgeranyl, transport protein, phosphodiesterase 6, rhodopsin, membrane dissociation, apo-state, membrane trafficking, cellular trafficking, rhodopsin kinase, ras-gtpase |
由来する生物種 | Mus musculus (Mouse) |
細胞内の位置 | Cytoplasm, cytosol : O55057 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 19540.31 |
構造登録者 | |
主引用文献 | Qureshi, B.M.,Schmidt, A.,Behrmann, E.,Burger, J.,Mielke, T.,Spahn, C.M.T.,Heck, M.,Scheerer, P. Mechanistic insights into the role of prenyl-binding protein PrBP/ delta in membrane dissociation of phosphodiesterase 6. Nat Commun, 9:90-90, 2018 Cited by PubMed: 29311697DOI: 10.1038/s41467-017-02569-y 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.81 Å) |
構造検証レポート
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