5T4J
PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation
Summary for 5T4J
Entry DOI | 10.2210/pdb5t4j/pdb |
Descriptor | HTH-type transcriptional regulatory protein GabR, PYRIDOXAL-5'-PHOSPHATE, GAMMA-AMINO-BUTANOIC ACID, ... (4 entities in total) |
Functional Keywords | gabr, mocr, plp, gaba, external aldimine, transcription regulator |
Biological source | Bacillus subtilis |
Total number of polymer chains | 1 |
Total formula weight | 42267.26 |
Authors | Wu, R.,Sanishvili, R.,Belitsky, B.R.,Juncosa, J.I.,Le, H.V.,Lehrer, H.J.S.,Farley, M.,Silverman, R.B.,Petsko, G.A.,Ringe, D.,Liu, D. (deposition date: 2016-08-29, release date: 2017-03-29, Last modification date: 2023-11-15) |
Primary citation | Wu, R.,Sanishvili, R.,Belitsky, B.R.,Juncosa, J.I.,Le, H.V.,Lehrer, H.J.,Farley, M.,Silverman, R.B.,Petsko, G.A.,Ringe, D.,Liu, D. PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114:3891-3896, 2017 Cited by PubMed: 28348215DOI: 10.1073/pnas.1703019114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.231 Å) |
Structure validation
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