5T3X
3.9 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074.
これはPDB形式変換不可エントリーです。
5T3X の概要
エントリーDOI | 10.2210/pdb5t3x/pdb |
関連するPDBエントリー | 5T3Z |
分子名称 | Envelope glycoprotein gp160, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (23 entities in total) |
機能のキーワード | hiv, n-linked glycosylation, broadly neutralizing antibodies, viral protein-immune system complex, viral protein/immune system |
由来する生物種 | Human immunodeficiency virus 1 詳細 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 189016.93 |
構造登録者 | |
主引用文献 | Gristick, H.B.,von Boehmer, L.,West, A.P.,Schamber, M.,Gazumyan, A.,Golijanin, J.,Seaman, M.S.,Fatkenheuer, G.,Klein, F.,Nussenzweig, M.C.,Bjorkman, P.J. Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat.Struct.Mol.Biol., 23:906-915, 2016 Cited by PubMed: 27617431DOI: 10.1038/nsmb.3291 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.9 Å) |
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