5T2K

Geobacillus stearothermophilus HemQ with Manganese-Coproporphyrin III

Summary for 5T2K

• Entry DOI: 10.2210/pdb5t2k/pdb
• Descriptor: Putative heme-dependent peroxidase GT50_08830, [3,3',3'',3'''-(3,8,13,17-tetramethylporphyrin-2,7,12,18-tetrayl-kappa~4~N~21~,N~22~,N~23~,N~24~)tetra(propanoato)(2-)]manganese (3 entities in total)
• Functional Keywords: hemq, coproporphyrin iii, decarboxylation, oxidoreductase
• Biological source: Geobacillus stearothermophilus 10
• Total number of polymer chains: 5
• Total formula weight: 147626.20

Authors

Gauss, G.H.,Celis, A.I.,Dubois, J.L.,Peters, J.W. (deposition date: 2016-08-23, release date: 2017-01-18, Last modification date: 2023-10-04)

• Primary citation: Celis, A.I.,Gauss, G.H.,Streit, B.R.,Shisler, K.,Moraski, G.C.,Rodgers, K.R.,Lukat-Rodgers, G.S.,Peters, J.W.,DuBois, J.L.; Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ).; J. Am. Chem. Soc., 139:1900-1911, 2017; PubMed: 27936663; DOI: 10.1021/jacs.6b11324

Experimental method

X-RAY DIFFRACTION (1.8 Å)