5T05

Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate

5T05 の概要

• エントリーDOI: 10.2210/pdb5t05/pdb
• 関連するPDBエントリー: 5T03 5T0A
• 関連するBIRD辞書のPRD_ID: PRD_900010
• 分子名称: maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: heparan sulfate, sulfotransferase, complex, transferase
• 由来する生物種: Escherichia coli O157:H7; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 164114.51

構造登録者

Pedersen, L.C.,Moon, A.F.,krahn, J.M.,Liu, J. (登録日: 2016-08-15, 公開日: 2017-02-01, 最終更新日: 2020-07-29)

• 主引用文献: Xu, Y.,Moon, A.F.,Xu, S.,Krahn, J.M.,Liu, J.,Pedersen, L.C.; Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.; ACS Chem. Biol., 12:73-82, 2017; PubMed: 28103688; DOI: 10.1021/acschembio.6b00841

実験手法

X-RAY DIFFRACTION (1.952 Å)