5SZX

Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA

Summary for 5SZX

• Entry DOI: 10.2210/pdb5szx/pdb
• Related: 5T01
• Descriptor: DNA (5'-D(*TP*CP*TP*TP*CP*AP*TP*(5CM)P*GP*CP*TP*CP*AP*GP*TP*GP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*GP*(5CM)P*GP*AP*TP*GP*AP*AP*G)-3'), Zta transcription factor, ... (5 entities in total)
• Functional Keywords: zta, zebra, bzlf-1, ap-1, epstein-barr virus, ebv, 5-methylcytosine, 5mc, dna methylation, transcription factor, basic leucine-zipper, bzip, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Epstein-Barr virus (HHV-4, Human herpesvirus 4); More
• Total number of polymer chains: 4
• Total formula weight: 25752.29

Authors

Hong, S.,Horton, J.R.,Cheng, X. (deposition date: 2016-08-15, release date: 2017-03-01, Last modification date: 2023-10-04)

• Primary citation: Hong, S.,Wang, D.,Horton, J.R.,Zhang, X.,Speck, S.H.,Blumenthal, R.M.,Cheng, X.; Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.; Nucleic Acids Res., 45:2503-2515, 2017; PubMed: 28158710; DOI: 10.1093/nar/gkx057

Experimental method

X-RAY DIFFRACTION (2.251 Å)