5SZT

Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentenyl)-7-deaza-2'-dATP

5SZT の概要

• エントリーDOI: 10.2210/pdb5szt/pdb
• 分子名称: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
• 機能のキーワード: linker-modified nucleotide, klentaq, dna polymerase, transferase
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 70730.39

構造登録者

Hottin, A.,Betz, K.,Marx, A. (登録日: 2016-08-15, 公開日: 2016-12-14, 最終更新日: 2024-01-17)

• 主引用文献: Hottin, A.,Betz, K.,Diederichs, K.,Marx, A.; Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.; Chemistry, 23:2109-2118, 2017; PubMed: 27901305; DOI: 10.1002/chem.201604515

実験手法

X-RAY DIFFRACTION (1.8 Å)