5SYC
Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule
Summary for 5SYC
Entry DOI | 10.2210/pdb5syc/pdb |
Related | 5SYE 5SYF 5SYG |
EMDB information | 8320 8321 8322 8323 |
Descriptor | Tubulin alpha chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | peloruside, microtubule, structural protein |
Biological source | Sus scrofa (Pig) More |
Total number of polymer chains | 2 |
Total formula weight | 98044.26 |
Authors | Kellogg, E.H.,Nogales, E. (deposition date: 2016-08-10, release date: 2017-02-01, Last modification date: 2024-03-06) |
Primary citation | Kellogg, E.H.,Hejab, N.M.,Howes, S.,Northcote, P.,Miller, J.H.,Diaz, J.F.,Downing, K.H.,Nogales, E. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429:633-646, 2017 Cited by PubMed: 28104363DOI: 10.1016/j.jmb.2017.01.001 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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