5SWE

Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography

5SWE の概要

• エントリーDOI: 10.2210/pdb5swe/pdb
• 関連するPDBエントリー: 5E54 5SWD
• 分子名称: Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain, ADENINE (2 entities in total)
• 機能のキーワード: adenine riboswitch, purine riboswitch, ligand mixing, rna, gene regulation, x-ray free electron laser
• 由来する生物種: Vibrio vulnificus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22822.51

構造登録者

Stagno, J.R.,Wang, Y.-X.,Liu, Y.,Bhandari, Y.R.,Conrad, C.E.,Nelson, G.,Li, C.,Wendel, D.R.,White, T.A.,Barty, A.,Tuckey, R.A.,Zatsepin, N.A.,Grant, T.D.,Fromme, P.,Tan, K.,Ji, X.,Spence, J.C.H. (登録日: 2016-08-08, 公開日: 2016-11-23, 最終更新日: 2023-10-04)

• 主引用文献: Stagno, J.R.,Liu, Y.,Bhandari, Y.R.,Conrad, C.E.,Panja, S.,Swain, M.,Fan, L.,Nelson, G.,Li, C.,Wendel, D.R.,White, T.A.,Coe, J.D.,Wiedorn, M.O.,Knoska, J.,Oberthuer, D.,Tuckey, R.A.,Yu, P.,Dyba, M.,Tarasov, S.G.,Weierstall, U.,Grant, T.D.,Schwieters, C.D.,Zhang, J.,Ferre-D'Amare, A.R.,Fromme, P.,Draper, D.E.,Liang, M.,Hunter, M.S.,Boutet, S.,Tan, K.,Zuo, X.,Ji, X.,Barty, A.,Zatsepin, N.A.,Chapman, H.N.,Spence, J.C.,Woodson, S.A.,Wang, Y.X.; Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.; Nature, 541:242-246, 2017; PubMed: 27841871; DOI: 10.1038/nature20599

実験手法

X-RAY DIFFRACTION (3 Å)