5SWB

Crystal structure of N-glycan transport solute binding protein (NgtS) from Streptococcus pneumoniae in complex with Man5GlcNAc

Summary for 5SWB

• Entry DOI: 10.2210/pdb5swb/pdb
• Related: 5SWA 5SWI
• Descriptor: Extracellular solute-binding protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-5)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: solute binding protein, protein-glycan complex, alpha/beta domain, hydrolase
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 4
• Total formula weight: 221120.75

Authors

Robb, M.,Boraston, A.B. (deposition date: 2016-08-08, release date: 2016-12-14, Last modification date: 2023-10-04)

• Primary citation: Robb, M.,Hobbs, J.K.,Woodiga, S.A.,Shapiro-Ward, S.,Suits, M.D.,McGregor, N.,Brumer, H.,Yesilkaya, H.,King, S.J.,Boraston, A.B.; Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence.; PLoS Pathog., 13:e1006090-e1006090, 2017; PubMed: 28056108; DOI: 10.1371/journal.ppat.1006090

Experimental method

X-RAY DIFFRACTION (1.73 Å)