5SUR

X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36. Synchrotron data set. (ORN)CVF(MEA)CED(ORN)AIIGL(ORN)V.

Summary for 5SUR

• Entry DOI: 10.2210/pdb5sur/pdb
• Related: 5SUS 5SUT 5SUU
• Descriptor: 16mer A-beta peptide: ORN-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORN-ALA-ILE-ILE-GLY-LEU-ORN-VAL, SODIUM ION, HEXANE-1,6-DIOL, ... (5 entities in total)
• Functional Keywords: amyloid, oligomer, alzheimer's, trimer, protein fibril, de novo protein
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 7730.30

Authors

Kreutzer, A.G.,Yoo, S.,Nowick, J.S. (deposition date: 2016-08-03, release date: 2017-01-11, Last modification date: 2024-03-27)

• Primary citation: Kreutzer, A.G.,Yoo, S.,Spencer, R.K.,Nowick, J.S.; Stabilization, Assembly, and Toxicity of Trimers Derived from A beta.; J.Am.Chem.Soc., 139:966-975, 2017; PubMed: 28001392; DOI: 10.1021/jacs.6b11748

Experimental method

X-RAY DIFFRACTION (1.801 Å)