5RGE
Crystal Structure of Kemp Eliminase HG3.17 with bound transition state analog, 277K
Summary for 5RGE
| Entry DOI | 10.2210/pdb5rge/pdb |
| Group deposition | Crystal structures of HG-series of Kemp Eliminases at Room-temperature (G_1002148) |
| Descriptor | Kemp Eliminase HG3, 6-NITROBENZOTRIAZOLE (3 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | Thermoascus aurantiacus |
| Total number of polymer chains | 1 |
| Total formula weight | 34639.97 |
| Authors | Broom, A.,Rakotoharisoa, R.V.,Thompson, M.C.,Fraser, J.S.,Chica, R.A. (deposition date: 2020-03-19, release date: 2020-07-22, Last modification date: 2024-03-06) |
| Primary citation | Broom, A.,Rakotoharisoa, R.V.,Thompson, M.C.,Zarifi, N.,Nguyen, E.,Mukhametzhanov, N.,Liu, L.,Fraser, J.S.,Chica, R.A. Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11:4808-4808, 2020 Cited by PubMed: 32968058DOI: 10.1038/s41467-020-18619-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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