5R4Y

XChem fragment screen -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF THE HUMAN ATAD2 in complex with N13612a

Summary for 5R4Y

• Entry DOI: 10.2210/pdb5r4y/pdb
• Group deposition: XChem fragment screen (G_1002130)
• Descriptor: ATPase family AAA domain-containing protein 2, cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone, SULFATE ION, ... (5 entities in total)
• Functional Keywords: pandda, sgc - diamond i04-1 fragment screening, xchemexplorer, atpase family, aaa domain containing 2, ancca, aaa+ nuclear coregulator cancer-associated pro2000 protein, two aaa domain containing protein, sgc, structural genomics consortium, atp-binding, bromodomain, nucleotide-binding, phosphoprotein, signaling protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16201.26

Authors

Talon, R.,Krojer, T.,Fairhead, M.,Sethi, R.,Bradley, A.R.,Aimon, A.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Wright, N.,MacLean, E.,Zhang, R.,Dias, A.,Brennan, P.E.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F. (deposition date: 2020-02-28, release date: 2020-05-13, Last modification date: 2024-03-06)

• Primary citation: Talon, R.,Krojer, T.,Fairhead, M.,Sethi, R.,Bradley, A.R.,Aimon, A.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Wright, N.,MacLean, E.,Zhang, R.,Dias, A.,Brennan, P.E.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F.; XChem fragment screen; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.84 Å)