5R4S

PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45

Summary for 5R4S

• Entry DOI: 10.2210/pdb5r4s/pdb
• Group deposition: PanDDA analysis group deposition (G_1002126)
• Descriptor: Cleavage and polyadenylation specificity factor subunit 5, (4S,5R)-4-hydroxy-5-methyl-5-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]pyrrolidin-2-one, ZINC ION, ... (5 entities in total)
• Functional Keywords: pandda, sgc - diamond i04-1 fragment screening, nudix domain, xchemexplorer, cpsf5, rna processing, cleavage factor, mrna processing, nucleus, phosphoprotein, rna-binding, rna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 46590.67

Authors

Kidd, S.L.,Mateu, N.,Talon, R.,Krojer, T.,Aimon, A.,Bradley, A.R.,Fairhead, M.,Diaz-Saez, L.,Sore, H.F.,Madin, A.,Huber, K.V.M.,von Delft, F.,Spring, D.R. (deposition date: 2020-02-27, release date: 2020-07-08, Last modification date: 2024-03-06)

• Primary citation: Kidd, S.L.,Mateu, N.,Talon, R.,Krojer, T.,Aimon, A.,Bradley, A.R.,Fairhead, M.,Diaz-Saez, L.,Sore, H.F.,Madin, A.,Huber, K.V.M.,von Delft, F.,Spring, D.R.; PanDDA analysis group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)