5R1H
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 32, DMSO-free
Summary for 5R1H
Entry DOI | 10.2210/pdb5r1h/pdb |
Group deposition | PanDDA analysis of F2X-Entry Screen vs. Aar2/RNaseH, DMSO-free soaking (G_1002119) |
Descriptor | Pre-mRNA-splicing factor 8, A1 cistron-splicing factor AAR2 (3 entities in total) |
Functional Keywords | fragmax, fragmaxapp, fragment screening, rnaseh like domain, vhs like domain, u5 snrnp assembly, splicing |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 65710.95 |
Authors | Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G.,Weiss, M.S. (deposition date: 2020-02-12, release date: 2020-06-03, Last modification date: 2021-03-10) |
Primary citation | Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G.,Weiss, M.S. F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28:694-706.e5, 2020 Cited by PubMed: 32413289DOI: 10.1016/j.str.2020.04.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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