5QYB

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a

Summary for 5QYB

• Entry DOI: 10.2210/pdb5qyb/pdb
• Group deposition: PanDDA analysis of F2X-Entry vs. Aar2/RNaseH (G_1002115)
• Descriptor: Pre-mRNA-splicing factor 8, A1 cistron-splicing factor AAR2, (3-methoxyphenyl)(pyrrolidin-1-yl)methanone, ... (5 entities in total)
• Functional Keywords: fragmax, fragmaxapp, fragment screening, rnaseh like domain, vhs like domain, u5 snrnp assembly, splicing, f2x-entry
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 66108.33

Authors

Weiss, M.S.,Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G. (deposition date: 2020-02-12, release date: 2020-06-10)

• Primary citation: Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G.,Weiss, M.S.; F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.; Structure, 28:694-706.e5, 2020; PubMed: 32413289; DOI: 10.1016/j.str.2020.04.019

Experimental method

X-RAY DIFFRACTION (2.1 Å)